Anastrozole pharmacokinetics Tren been investigated in postmenopausal female volunteers and patients with breast cancer. Estradiol and estrone sulfate serum levels were similar between Japanese and Caucasian postmenopausal women who received 1 mg of Anastrozole daily for 16 days. Anastrozole mean steady-state minimum plasma concentrations in Caucasian and Japanese postmenopausal women were Anastrozole pharmacokinetics have been investigated in subjects with Trenbolone in UK impairment. No dosage adjustment is needed for renal impairment [ see Dosage and Administration 2. Anastrozole pharmacokinetics have been investigated in subjects with hepatic cirrhosis related to alcohol abuse. However, these plasma concentrations were still with the range of values observed in normal subjects. The effect of severe hepatic impairment was not studied. No dose adjustment is necessary for stable hepatic cirrhosis [ see Dosage and Administration 2.